Stannous Chloride: A Reagent for Removal of Dimethoxytrityl Group from 5'-Dimethoxytrityl Nucleosides
نویسندگان
چکیده مقاله:
Detritylation of 5'-dimethoxytrityl nucleosides have been quantitatively achieved in minutes at room temperature under aprotic neutral conditions by using stannous chloride. Of additional practical consideration and in contrast to protic acids, no depurination was observed with this reagent.
منابع مشابه
stannous chloride: a reagent for removal of dimethoxytrityl group from 5'-dimethoxytrityl nucleosides
detritylation of 5'-dimethoxytrityl nucleosides have been quantitatively achieved in minutes at room temperature under aprotic neutral conditions by using stannous chloride. of additional practical consideration and in contrast to protic acids, no depurination was observed with this reagent.
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عنوان ژورنال
دوره 17 شماره 2
صفحات 58- 60
تاریخ انتشار 1998-12-01
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